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Cosmetic Grade Polydeoxyribonucleotide PDRN Raw Material for Anti-aging Skincare Formulations

Product Name:Polydeoxyribonucleotide(PDRN)

INCI Name: DHA Na

Source: Male Salom

CAS No.: 100403-24-5

Appearance: White or light yellow powder or granules

Assay: 99%

Grade: Cosmetic grade

Solubility:Soluble in water

    Product Description

    The Chinese name of PDRN is "polydeoxyribonucleotide". It is a DNA fragment of specific specifications extracted from salmon testes. It is one of the complexes that generate DNA raw materials. It has the function of promoting tissue regeneration and effectively relieving inflammation, especially in human ligaments, tendons and skin. Based on its excellent efficacy, PDRN is widely used in the medical and aesthetic fields as a new raw material in the field of regenerative medicine. Eye drops, joint injections, medical devices in the field of medical beauty, cosmetics, food, etc. In recent years, PDRN mesotherapy has become one of the most popular technologies for skin clinics and plastic surgery in South Korea.
    Item Specification Test Method
    Physical&Chemical Control
    Appearance White or light yellow powder or granules Organoleptic
    Solubility Soluble in water In-House
    Identification

    UV: Ratio of absorbance at 260 and 280nm 1.8-2.0

    In-House
    Assay(On a dry basis) ≥99.0% UV
    PH 6.0-8.0 In-House
    Molecular weight 60-100 Kda In-House
    Particle Size 100% Pass 80 Mesh 80 Mesh Screen
    Loss on Drying ≤10.0% In-House
    Protein(BCA) ≤1.0% In-House
    Heavy Metals
    Lead(Pb) NMT 10 ppm In-House
    Arsenic(As) NMT 2ppm In-House
    Mercury(Hg) NMT 1 ppm In-House
    Cadmium(Cd) NMT 5 ppm In-House
    Microbiology Control
    Total Plate Count NMT3,000cfu/g CP2020
    Total Yeast & Mold NMT300cfu/g CP2020
    E.coli Negative CP2020
    Salmonella Negative CP2020
    Staphylococcus Negative CP2020

    Product Function

    1.Powerful Tissue Regeneration & Wound Healing: The core function of PDRN is to significantly accelerate tissue repair and wound healing. It provides the raw nucleotides necessary for damaged cells to regenerate more efficiently, promoting the growth of new skin cells, blood vessels (angiogenesis), and collagen fibers. This leads to faster recovery and improved healing outcomes.

    2.Anti-Inflammatory & Anti-Pain Effects: By binding to and activating the A2A receptor, PDRN exerts a potent anti-inflammatory effect, significantly reducing swelling, redness, and pain associated with tissue damage, surgical procedures, or chronic inflammatory conditions.

    3.Skin Rejuvenation & Anti-Aging: PDRN is renowned for its exceptional ability to stimulate fibroblasts to produce new collagen, elastin, and hyaluronic acid. This results in profound skin rejuvenation, improving skin elasticity, reducing the appearance of fine lines and wrinkles, and enhancing overall skin texture and firmness for a more youthful appearance.

    4.Cellular Energy & Repair: It serves as an energy source for damaged cells, enhancing cellular metabolism and promoting the survival and repair of tissues in a hypoxic (low-oxygen) or stressed environment.
    PDRN(Polydeoxyribonucleotide)

    Product Application

    1.Aesthetic & Regenerative Medicine: Used in microneedling, mesotherapy, and injectable treatments for facial rejuvenation, improving skin quality, hair restoration (for androgenetic alopecia), and reducing scars and stretch marks.

    2.Wound Care & Dermatology: Applied in the treatment of chronic, non-healing wounds (e.g., diabetic ulcers, pressure sores), burns, and post-surgical scars to accelerate closure and improve the quality of healed tissue.

    3.Orthopedics & Sports Medicine: Injected into joints (intra-articular injections) for tendinopathies, osteoarthritis, and ligament injuries to reduce pain and inflammation and promote the regeneration of cartilage and connective tissue.

    4.Ophthalmology: Used in eye drops for the treatment of corneal ulcers and dry eye disease to support corneal healing and reduce inflammation.
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